SAM Rainsyសហស្ថាបនិកគណបក្សសង្គ្រោះជាតិ

មូលហេតុចម្បង ដែលជនជាតិខ្មែរ មិនសូវឈឺពីជំងឺកូវីដ-១៩ / Cambodians' genetic protective factor (*)

ចែករំលែក ៖​

១៤ វិច្ឆិកា ២០២០ / 14 November 2020 - Cambodians' genetic protective factor (*)

មូលហេតុចម្បង ដែលជនជាតិខ្មែរ មិនសូវឈឺពីជំងឺកូវីដ-១៩ គឺដោយសារតែជនជាតិខ្មែរ តាំងពីសម័យអង្គរម្លេះ មានគ្រាប់ឈាមក្រហមពិសេស ដែលក្នុងនោះ មានសារជាតិ មិនធម្មតា (តែមិនមែនជាជំងឺទេ) ហៅថា អេម៉ូក្លូប៊ីន អឺ (Hémoglobine E) ដូចអ្វីដែលលោក សម រង្ស៊ី បានពន្យល់ តាមរយៈឯកសារវិទ្យាសាស្ត្រ ដែលលោកបានបង្ហោះ លើទំព័រ Facebook របស់លោក ដូច ត ទៅ ៖

(*) To understand why populations of Khmer descent are relatively spared from COVID-19 thanks to their hemoglobin E, please go to:

- ថ្ងៃ ១៨ ឧសភា ២០២០ / 18 May 2020
https://www.facebook.com/media/set/?vanity=rainsy.sam.5&set=a.3108295359227176

- ថ្ងៃ ៣១ ឧសភា ២០២០ / 31 May 2020
https://www.facebook.com/rainsy.sam.5/photos/3138445866212125

- ថ្ងៃ ០៩ មិថុនា ២០២០ / 09 June 2020
https://www.facebook.com/rainsy.sam.5/photos/3161270397263005

- ថ្ងៃ ២៨ មិថុនា ២០២០ / 28 June 2020 
https://www.facebook.com/rainsy.sam.5/photos/3211380875585290

ទោះជាយ៉ាងណាក៏ដោយ សូមរក្សាភាពប្រុងប្រយ័ត្ន ជានិច្ច !
In all cases, please remain careful and watchful!

A GENETIC PROTECTIVE FACTOR OR CROSS IMMUNITIES OR BOTH?

Observers are increasingly asking this question: "Why do Cambodians resist COVID-19 so well even while foreigners who have coronavirus could have transmitted it to them while visiting or passing through our country?"
The answer is probably related to genetic factors which I have already explained, and notably hemoglobin E, which has been described by leading scientists as a characteristic of the Khmer race.

Since the start of the pandemic almost a year ago, Cambodia has not suffered a single death nor even a severe case of COVID-19.  
Hemoglobin E has given protection against the most severe forms of malaria since the Angkor era, and seems also to protect against serious cases of COVID-19. It is interesting to note that the worst cases of malaria and COVID-19 have strikingly similar pathological symptoms: thrombosis (formation of blood clots), pulmonary embolism and strokes.
Cross immunities are being talked about more and more. Is there any reason why partial immunity to malaria would give at least partial immunity to COVID-19? Further evidence for the existence of cross immunity comes from Africa, where areas where malaria is endemic are resisting COVID-19 relatively well.

UN FACTEUR GÉNÉTIQUE PROTECTEUR, DES IMMUNITÉS CROISÉES OU LES DEUX A LA FOIS?
 Les observateurs se posent de plus en plus cette question: "Pourquoi les Cambodgiens résistent-ils si bien à la COVID-19 alors que des étrangers contaminés par le coronavirus auraient pu leur transmettre la maladie lors de leur visite ou passage dans notre pays?"
La réponse tient probablement à des facteurs génétiques que j'ai déjà exposés, notamment ceux ayant trait à l'hémoglobine E que de grands savants français comme le Professeur Jean Bernard ont décrite comme une caractéristique de la race khmère.
Rappelons que depuis le début la pandémie il y a presqu'un an, le Cambodge ne déplore aucun décès et on n'y a relevé aucun cas sévère de COVID-19. 

L'hémoglobine E qui protègerait les Khmers contre les formes les plus sévères du paludisme depuis l'époque d'Angkor, protégerait aussi les Cambodgiens maintenant contre les formes les sévères de la COVID-19. Il est intéressant de noter que les formes les plus sévères des deux maladies (paludisme et COVID-19) présentent des similitudes pathologiques frappantes: thrombose (formation de caillots de sang), embolies pulmonaires, accidents vasculaires cérébraux (AVC). 

Par ailleurs, on parle de plus en plus d'immunités croisées pour expliquer la résistance de certaines personnes à la COVID-19. Pourquoi une immunité partielle contre le paludisme ne conférerait-elle pas une forme d'immunité, au moins partielle aussi, contre la COVID-19? Les régions d'Afrique où le paludisme sévit d'une manière endémique et qui  résistent relativement bien à la COVID-19, présenteraient d'autres exemples d'immunités croisées.